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In 1990, Frosst et al (28) identified a C677T polymorphism in the MTHFR gene that reduced enzyme activity and altered folate concentrations
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For MS1 scan events, scan range of m/z 1001500, mass resolution of 17.5K, AGC of 1e 6 and inject time of 50 ms was used

B.CuddahyT.BriscellaC.RossN.OlszanskiA
Biomembr 52 (4), 247256